Liste des publications

2022

C. Van Wesemael, N. Brach, M. Gulea, G. Blond (2022). Gold(I)-Catalyzed Carbothiolation via Rearrangement of S-Propargyl Group: An Access to 3-Allenyl or 3-Indenyl Benzo[b]thiophenes. Adv. Synth. Catal. 2022 (selected VIP) https://doi.org/10.1002/adsc.202201000

Moeglin E., Barret L., Chatton B., Donzeau M. (2022).Modular Site-Specific Conjugation of Nanobodies Using Two Co-Associating Tags.Int. J. Molécular Sciences23(22), 14405. DOI:10.3390/ijms232214405

Moynié, L.; Hoegy, F.; Milenkovic, S.; Munier, M.; Paulen, A. ; Gasser, V.; Faucon, A.; Zill, N.; Naismith, J.H.; Ceccarelli, M.; Schalk, I.J. Mislin, G.L.A (2022). Hijacking of the enterobactin pathway by a synthetic catechol vector designed for oxazolidinone antibiotic delivery in Pseudomonas aeruginosa. ACS Infect. Dis. 2022, 8, 1894 (Cover page). doi.org/10.1021/acsinfecdis.2c00202

Normant , V. ; Kuhn, L.; Munier, M. ; Hammann, P. ; Mislin, G.L.A. ; Schalk, I.J. (2022). How the Presence of Hemin Affects the Expression of the Different Iron Uptake Pathways in Pseudomonas aeruginosa Cells.ACS Infect. Dis. 2022, 8, 183 (Cover page) doi.org/10.1021/acsinfecdis.1c00525

A Brion, J Chaud, J Léonard, F Bolze, S Chassaing, B Frisch, B Heurtault, A Kichler, A Specht. Red Light-Responsive Upconverting Nanoparticles for Quantitative and Controlled Release of a Coumarin-Based Prodrug. Advanced Healthcare Materials, 2022 Oct 12:e2201474. doi: 10.1002/adhm.202201474.

C McCartin, C Dussouillez, C Bernhard, E Mathieu, J Blumberger, M Dontenwill, C Herold-Mende, A Idbaih, P Lavalle, S Bellemin-Laponnaz, A Kichler, S Fournel. Polyethylenimine, an autophagy inducing platinum-carbene-based drug carrier with potent toxicity towards glioblastoma cancer stem cells. Cancers (Basel), 2022 Oct 15;14(20):5057. doi: 10.3390/cancers14205057.

C McCartin, E Mathieu, M Dontenwill, C Herold-Mendee, A Idbaihf, A Bonfigliog, M Mauro, S Fournel, A Kichler. An N-heterocyclic carbene iridium(III) complex as a potent anti-cancer stem cell therapeutic.Chemico-Biological Interactions, 2022, 367:110167. doi: 10.1016/j.cbi.2022.110167.

Arezki Y., Delalande F., Schaeffer C., Rapp M., Lebeau L., Pons F., Ronzani C. (2022). Surface charge influences protein corona, cell uptake and biological effects of carbon dots.Nanoscale. 14, 14695. DOI:10.1039/D2NR03611H

Maujean T., Marchand P., Wagner P., Girard N., Riché S., Boisson F., Bonnet D., Gulea M. (2022). Hetero-Diels-Alder Click Reaction of Dithioesters for a Catalyst-Free Indirect 18F-Radiolabelling of Peptides. Chem. Commun. 2022. DOI:10.1039/D2CC04148K

Choury M., Wagner P., Rognan C., Blond G., Gulea M. (2022). Access to 1,4-Thiazepanes via Gold-Catalyzed 7-exo-dig Thioallylation and their Cycloisomerization to Bicyclic [4.3.1] Bridgehead-Olefinic Systems. Adv. Synth. Catal. 2022 (selected VIP) DOI:10.1002/adsc.202200660

Arezki Y., Rapp M., Lebeau L., Ronzani C., Pons F. (2022). Cationic Carbon Nanoparticles Induce Inflammasome-Dependent Pyroptosis in Macrophages via Lysosomal Dysfunction.Front Toxicol. 4:925399. DOI:10.3389/ftox.2022.925399

Sonntag T., Rapp M., Didier P., Lebeau L., Pons F., Casset A. (2022). Mucus producing epithelial models for investigating the activity of gene delivery systems in the lung.  Int. J. Pharm. 614:121423. DOI:10.1016/j.ijpharm.2021.121423

Sani S., Pallaoro N., Messe M., Bernhard C., Etienne-Selloum N., Kessler H., Marinelli L., Entz-Werle N., Foppolo S., Martin S., Reita D., Dontenwill M. (2022). Temozolomide-Acquired Resistance Is Associated with Modulation of the Integrin Repertoire in Glioblastoma, Impact of α5β1 Integrin. Cancers (Basel). 12;14(2):369. DOI:10.3390/cancers14020369

Ali S., Dussouillez C., Padilla B., Frisch B., Mason A.J., Kichler A. (2022). Design of a new cell penetrating peptide for DNA, siRNA and mRNA deliveryJ Gene Med. 24(3):e3401. DOI:10.1002/jgm.3401

Herrscher V., Witjaksono C., Buchotte M., Ferret C., Massicot F., Vasse J.L., Borel F., Behr J.B., Seemann M. (2022). Irreversible inhibition of IspG, a target for the development of new antimicrobials, by a 2-vinyl analogue of its MEcPP substrate. Chem. Eur. J. (accepted article). DOI:10.1002/chem.202200241

Jobelius H., Bianchino G.I., Borel F., Chaignon P., Seemann M. (2022). The Reductive Dehydroxylation Catalyzed by IspH, a Source of Inspiration for the Development of Novel Anti-Infectives. Molecules. 27(3), 708. DOI:10.3390/molecules27030708

Aline L.Faucon, Françoise Hoegy, Noémie Werle, Christophe Gourlaouen, Gaëtan L.A. Mislin (2022). Dipyridylamine-acetamide (Dpaa): A primary amine protecting group orthogonally cleavable under acidic conditions in the presence of t-butyloxycarbonyl (Boc) and t-butylester. Tet. Lett., 96, 153758. DOI: 10.1016/j.tetlet.2022.153758

Roméric Galéa, Gaëlle Blond (2022). Gold(I)-Catalyzed Domino Reaction: An Access to Furooxepines. Adv. Synth. Catal. 2022, 364, 1532. DOI: 10.1002/adsc.202200019

2021

Kouijzer, J.J.P. ; Lattwein, K.R.; Beekers, I. ; Langeveld, S.A.G. ; Leon-Grooters, M. ; Strub, J.-M. ; Oliva, E. ; Mislin, G.L.A. ; de Jong, N. ; van der Steen, A.F.W. ; Klibanov, A.L. ; van Wamel, W.J.B. ; Kooiman, K. (2021). Vancomycin-decorated microbubbles as a theranostic agent for Staphylococcus aureus biofilm. Int. J. Pharm. 2021, 121154. doi.org/10.1016/j.ijpharm.2021.121154.

Dietsch F., Nominé Y., Stoessel A., Kostmann C., Bonhoure A., Chatton B., Donzeau M. (2021). Small p53 derived peptide suitable for robust nanobodies dimerization. Journal of Immunological 498:112144. DOI:10.1016/j.jim.2021.113144

Arezki Y., Cornacchia J., Rapp M., Lebeau L., Pons F., Ronzani C. (2021). A co-culture model of the human respiratory tract to discriminate the toxicological profile of cationic nanoparticles according to their surface charge density. Toxics 9:210. DOI:10.3390/toxics9090210

Mauger M., Ferreri C., Chatgilialoglu C., Seemann M. (2021). The bacterial protective armor against stress: The cis-trans isomerase of unsaturated fatty acids, a cytochrome-c type enzyme. J. Inorg. Biochem. 224: 111564. DOI:10.1016/j.jinorgbio.2021.111564

Tetard A., Foley S., Mislin G.L.A., Brunel J.M., Oliva E., Torrealba Anzola F., Zedet A., Cardey B., Pellequer Y., Ramseyer C., Plésiat P., Llanes C. (2021). Negative impact of citral on cusceptibility of Pseudomonas aeruginosa to antibiotics. Front. Microbiol 12:709838. DOI:10.3389/fmicb.2021.709838

Michaut M., Steffen A., Contreras J.-M., Morice C., Schalk I.J., Plésiat P., Mislin G.L.A. (2021). 1,2,3-Triazole-gold(I)-triethylposphine derivatives active against resistant Gram-positive pathogens. Bioorg. Med. Chem. Lett. 40:127879. DOI:10.1016/j.bmcl.2021.127879

Perraud Q., Kuhn L., Fritsch S., Graulier G., Gasser V., Normant V., Hammann P., Schalk I.J. (2021). Opportunistic use of catecholamine neurotransmitters as siderophores to access iron by Pseudomonas aeruginosa. Environ. Microbiol.  24(2):878-893. DOI:10.1111/1462-2920.15372

Gasser V., Kuhn L., Hubert T., Aussel L., Hammann P., Schalk I.J. (2021). The esterase PfeE, the Achilles’ heel in the battle for iron between P. aeruginosa and E. coli. Int. J. Mol. Sci. 22(6):2814. DOI:10.3390/ijms22062814

Miethke M., Pieroni M., Weber T., Brönstrup M., Hammann P., Halby L., Arimondo P., Glaser P., Aigle B., Bode H., Moreira R., Li Y., Luzhetskyy A., Medema M., Pernodet J.-L., Stadler M., Tormo J., Genilloud O., Truman A., Weissman K., Takano E., Sabatini S., Stegmann E., Brötz-Oesterhelt H., Wohlleben W., Seemann M., Empting M., Hirsch A., Loretz B., Lehr C.-M., Titz A., Herrmann J., Jaeger T., Alt S., Hesterkamp T., Winterhalter M., Schiefer A., Pfarr K., Hoerauf A., Graz H., Graz M., Lindvall M., Ramurthy S., Karlén A., van Dongen M., Petković H., Keller A., Peyrane F., Donadio S., Fraisse L., Piddock L., Gilbert I., Moser H., Müller R. (2021). Towards the sustainable discovery and development of new antibiotics. Nat Rev Chem 5(10):726-749. DOI:10.1038/s41570-021-00313-1

Choury M., Blond G., Gulea M. (2021). A synthetic route to benzothiazocines with two or three carbon stereocenters via copper‐catalyzed intramolecular Narylation. Eur. J. Org. Chem. 2021:2203-2211. DOI:10.1002/ejoc.202100305

Mazzoleni M., Zimmermann-Meisse G., Smirnova A., Tarassov I., Prévost G. (2021). Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria. FASEB J. 35:e21167. DOI:10.1096/fj.201902981R

Le Guen C., Dussouillez C., Kichler A., Chan-Seng D. (2021). Insertion of hydrophobic spacers on dodecalysines as potential transfection enhancers. Eur. Polym. J. 157:110654. DOI:10.1016/j.eurpolymj.2021.110654

Spanedda M.V., Bourel-Bonnet L.(2021). Cyclic anhydrides as powerful tools for bioconjugation and smart delivery. Bioconjugate Chem. 32:482-496. DOI:10.1021/acs.bioconjchem.1c00023

Pozza M.D., Orvain C., Brustolin L., Pettenuzzo N., Nardon C., Gaiddon C., Fregona D. (2021). Gold(III) to ruthenium(III) metal exchange in dithiocarbamato complexes tunes their biological mode of action for cytotoxicity in cancer cellsMolecules 26:4073. DOI:10.3390/molecules26134073

Blanchet A., Bourgmayer A., Kurtz J.-E., Mellitzer G., and Gaiddon C. (2021). Isoforms of the p53 family and gastric cancer: a ménage à trois for an unfinished affair. Cancers 13:916. DOI:10.3390/cancers13040916

Gaiddon C., Gross I., Meng X., Sidhoum M, Mellitzer G, Romain B, Delhorme J.B., Venkatasamy A., Jung A., Pfeffer M. (2021). Bypassing the resistance mechanisms of the tumor ecosystem by targeting the endoplasmic reticulum stress pathway using ruthenium-and osmium-based organometallic compounds: An exciting long-term collaboration with Dr. Michel Pfeffer. Molecules 26(17):5386. DOI:10.3390/molecules26175386

Mueller C., Gaiddon C., Venkatasamy A. (2021). Current clinical and pre-clinical imaging approaches to study the cancer-associated immune system. Frontier Immunol. 12:716860. DOI:10.3389/fimmu.2021.716860

El Omar R., Julien E., Biasch K., Guffroy B., Lioure B., Vallat L., Gross I., Domon-Dell C., Lanza F., Gachet C., Negroni M., Freund J.-N., Tavian M. (2021). CDX2 regulates ACE expression in blood development and leukemia cells. Blood Adv. 5(7):2012-2016. DOI:10.1182/bloodadvances.2020003563

Dahlet T. , Truss M., Frede U., Al Adhami  H., Bardet A.F., Dumas M., Vallet J., Chicher J., Hammann P., Kottnik S., Hansen P., Luz U., Alvarez G., Auclair G., Hecht J., Robinson P.N., Hagemeier C., Weber M. (2021). E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Nat. Commun. 12:3582. DOI:10.1038/s41467-021-23596-w

Groysbeck N., Donzeau M., Stoessel A., Haeberlé A.M., Ory S., Spehner D., Schultz P., Ersen O., Bahri M., Ihiawakrim D. and Zuber G. (2021). Gold labelling of Green Fluorescent Protein (GFP)-tag inside cells using recombinant nanobodies conjugated to 2.4 nm thiolate-coated gold nanoparticules. Nanoscale Adv. 3:6940-6948. DOI:10.1039/D1NA00256B

2020

Manko H., Normant V., Perraud Q., Steffan T., Gasser V., Boutant E., Réal É., Schalk I.J., Mély Y., Godet J. (2020). FLIM-FRET Measurements of protein-protein interactions in live bacteria.J. Vis. Exp. 2020, 162. DOI:10.3791/61602

Maujean T., Chataigner I., Girard N., Gulea M., Bonnet D. (2020). Endocyclic enamides derived from aza-diketopiperazines as olefin partners in Povarov reaction: An access to tetracyclic N-heterocycles. Eur. J. Org. Chem. 2020:7385–7395. DOI:10.1002/ejoc.202001339

Olivares E., Tasse J., Badel-Berchoux S., Provot C., Prévost G., Bernardi T. (2020). Clinical Biofilm Ring Test® reveals the potential role of β-lactams in the induction of biofilm formation by P. aeruginosa in cystic fibrosis patients. Pathogens 9:1065. DOI:10.3390/pathogens9121065

Duvergé A., Negroni M. (2020). Pseudotyping lentiviral vectors: When the Clothes Make the Virus. Viruses 12:1311. DOI:10.3390/v12111311

Miller J., Gaiddon C., Storr T. (2020). A balancing act: Using small molecules for therapeutic intervention of the p53 pathway in cancer. Chem. Soc. Rev. 49:6995-7014. DOI:10.1039/d0cs00163e